Research Paper Volume 12, Issue 24 pp 25956—25980

Periodontitis in elderly patients with type 2 diabetes mellitus: impact on gut microbiota and systemic inflammation

Figure 1. Differences in gut microbiota profile among three groups. (A) OTU accumulation boxplot to show that the number of samples is adequate. (B) Principal Co-ordinates Analysis (PCoA) plot of weighted UniFrac distances. (C) Fecal microbiota composition at the phylum level among the three groups. (D) BugBase algorithm predicted that microbiota phenotypes of the T2DM_P group significantly differed from healthy volunteers in terms of gram-positive bacteria. (E) Heatmap of PICRUSt analysis shows significant KEGG pathways among the three groups.