Research Paper Volume 13, Issue 1 pp 750—768

KRAS mutations are negatively correlated with immunity in colon cancer

The landscape of genetic mutations in colon cancer. (A) The 30 most frequent mutations of samples in the ICGC database. The percentage of patients with mutations, translation effect (synonymous or non-synonymous), and mutation types were given. (B) The 30 most frequent mutations of samples in the TCGA database. (C) A Venn diagram of mutated genes. There were 17 genes that were members of the 30 most frequently mutated genes in the ICGC and TCGA databases.

Figure 1. The landscape of genetic mutations in colon cancer. (A) The 30 most frequent mutations of samples in the ICGC database. The percentage of patients with mutations, translation effect (synonymous or non-synonymous), and mutation types were given. (B) The 30 most frequent mutations of samples in the TCGA database. (C) A Venn diagram of mutated genes. There were 17 genes that were members of the 30 most frequently mutated genes in the ICGC and TCGA databases.