Research Paper Volume 13, Issue 1 pp 877—893

Coicis semen protects against focal cerebral ischemia-reperfusion injury by inhibiting oxidative stress and promoting angiogenesis via the TGFβ/ALK1/Smad1/5 signaling pathway

Coicis semen promoted angiogenesis after ischemic stroke. (A) Images showing CD31 detection in the ischemic penumbra via immunofluorescent staining and counterstaining with DAPI. (B) Quantification of CD31-positive cells in the ischemic penumbra. (C) VEGF levels were detected by ELISA. Mean ± SD. n = 5. aP t-test.

Figure 5. Coicis semen promoted angiogenesis after ischemic stroke. (A) Images showing CD31 detection in the ischemic penumbra via immunofluorescent staining and counterstaining with DAPI. (B) Quantification of CD31-positive cells in the ischemic penumbra. (C) VEGF levels were detected by ELISA. Mean ± SD. n = 5. aP < 0.05 vs. vehicle. Statistical analyses were performed by two-tailed Student’s t-test.