Research Paper Volume 13, Issue 1 pp 877—893

Coicis semen protects against focal cerebral ischemia-reperfusion injury by inhibiting oxidative stress and promoting angiogenesis via the TGFβ/ALK1/Smad1/5 signaling pathway

Coicis semen increased cell viability in HUVECs after OGD/RX. (A) Representative imaging showing CD31 detection in HUVECs after OGD/RX by using immunofluorescence staining. Mean ± SD. n = 5. aP bP B) Quantitative analysis of CD31-positive cells. (C) Quantitative analysis of cell viability in cells treated with Coicis Semen at different doses. Mean ± SD. n = 5. aP bP P #P

Figure 7. Coicis semen increased cell viability in HUVECs after OGD/RX. (A) Representative imaging showing CD31 detection in HUVECs after OGD/RX by using immunofluorescence staining. Mean ± SD. n = 5. aP < 0.05 vs. sham; bP < 0.05 vs. DMSO. Statistical analyses were performed by one-way ANOVA followed by Tukey’s multiple comparison tests. (B) Quantitative analysis of CD31-positive cells. (C) Quantitative analysis of cell viability in cells treated with Coicis Semen at different doses. Mean ± SD. n = 5. aP < 0.05 vs. sham; bP < 0.05 vs. DMSO; *P < 0.05 vs. Coicis Semen (400 μM); #P < 0.05 vs. Coicis Semen (600 μM). Statistical analyses were performed by one-way ANOVA followed by Tukey’s multiple comparison tests.