Research Paper Volume 13, Issue 1 pp 894—909

The emerging role of the MiR-1272-ADAM9-CDCP1 signaling pathway in the progression of glioma

MiR-1272 prohibits tumor proliferation and migration in glioma cells. (A) The expression of miR-1272 in HA1800, SHG44, A172, U251, LN229, and T98G cell lines was detected by qPT-PCR. (B) CCK-8 assay was applied to explore the effects of miR-1272 on the proliferation of glioma cells transfected with miR-1272 mimic or inhibitor. (C and D) Ectopic expression of miR-1272 inhibited the migration of glioma cells. Error bars represent mean ± SEM. NC, negative control. * p

Figure 1. MiR-1272 prohibits tumor proliferation and migration in glioma cells. (A) The expression of miR-1272 in HA1800, SHG44, A172, U251, LN229, and T98G cell lines was detected by qPT-PCR. (B) CCK-8 assay was applied to explore the effects of miR-1272 on the proliferation of glioma cells transfected with miR-1272 mimic or inhibitor. (C and D) Ectopic expression of miR-1272 inhibited the migration of glioma cells. Error bars represent mean ± SEM. NC, negative control. * p < 0.05, ** p < 0.01, *** p < 0.001.