Research Paper Volume 12, Issue 24 pp 25981—25999

Profilin 2 promotes growth, metastasis, and angiogenesis of small cell lung cancer through cancer-derived exosomes

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Figure 1.

PFN2 detected in SCLC tissue and normal lung tissue. IHC results showing PFN2 expression in SCLC tissues but not in the healthy lung and adjacent tissues (A). The ratio of PFN2 expression is dramatically higher in SCLC tissue than in normal lung tissue (P=0.0000) (B). Kaplan-Meier survival analysis reveals that PFN2 expression is inversely correlated with the survival time in patients with SCLC (C).