Research Paper Advance Articles

Exosomes derived from BDNF-expressing 293T attenuate ischemic retinal injury in vitro and in vivo

BDNF expression increased in 293T-Exo and 293T-Exo-treated R28 cells. mRNA (A) and protein (B) expressions of BDNF in control 293T cells, BDNF-expressing 293T cells, exosomes derived from control 293T cells, and BDNF-expressing 293T cells. mRNA (C) and protein (D) expressions in control R28 cells (R28), R28 cells treated with 293T-Exo-conditioned medium (R28+ CM), and R28 cells cocultured with 293T-Exo. Data are presented as mean ± SD. *P P

Figure 2. BDNF expression increased in 293T-Exo and 293T-Exo-treated R28 cells. mRNA (A) and protein (B) expressions of BDNF in control 293T cells, BDNF-expressing 293T cells, exosomes derived from control 293T cells, and BDNF-expressing 293T cells. mRNA (C) and protein (D) expressions in control R28 cells (R28), R28 cells treated with 293T-Exo-conditioned medium (R28+ CM), and R28 cells cocultured with 293T-Exo. Data are presented as mean ± SD. *P < 0.05, **P < 0.01.