Research Paper Advance Articles

Exosomes derived from BDNF-expressing 293T attenuate ischemic retinal injury in vitro and in vivo

293T-Exo inhibited OGD-induced cell death of R28 cells. (A) The percentage of EdU-positive in normoxic- or OGD-R28 cells with treatment of 293T-Exo, 293T-Exo-conditioned medium (293T-CM), and conditioned medium without 293T-Exo (CM-293T-Exo), as measured by flow cytometry. (B) Cell death rate was reduced by increasing concentration of 293T-Exo, as measured by the LDH assay. Data are presented as mean ± SD. *P

Figure 7. 293T-Exo inhibited OGD-induced cell death of R28 cells. (A) The percentage of EdU-positive in normoxic- or OGD-R28 cells with treatment of 293T-Exo, 293T-Exo-conditioned medium (293T-CM), and conditioned medium without 293T-Exo (CM-293T-Exo), as measured by flow cytometry. (B) Cell death rate was reduced by increasing concentration of 293T-Exo, as measured by the LDH assay. Data are presented as mean ± SD. *P < 0.05.