Research Paper Volume 12, Issue 24 pp 26029—26046

DUSP5 suppresses interleukin-1β-induced chondrocyte inflammation and ameliorates osteoarthritis in rats

Figure 7. Effect of QNZ and GDC on IL-1β-induced inflammation in DUSP5 knockdown chondrocytes. (A, B) The protein expression and quantitation of DUSP5, iNOS, COX2, and MMP9. (C, D) The protein expression and quantitation of DUSP5, iNOS, COX2, and MMP9. GAPDH was used as the control. DUSP5 knockdown chondrocytes were treated with 10 μM QNZ or 6.1 nM GDC for 2 h before incubation with IL-1β (10 ng/mL) for 24 h. All data are expressed as mean±S.D. (n = 3). *p<0.05, **p<0.01.