Research Paper Volume 13, Issue 1 pp 1212—1235

Therapeutic potential of targeting HSPA5 through dual regulation of two candidate prognostic biomarkers ANXA1 and PSAT1 in osteosarcoma

Significantly enriched pathways of DEGs in OS. (A, B) Representative GSEA of KEGG pathway gene set has04141 among DEGs from GSE16087 and GSE16088 datasets. (C, D) Heatmap analysis of shared DEGs enriched in KEGG pathway hsa04141 from the two GSE datasets. DEGs were defined with |log2FC| > 1 and adjusted P-value

Figure 2. Significantly enriched pathways of DEGs in OS. (A, B) Representative GSEA of KEGG pathway gene set has04141 among DEGs from GSE16087 and GSE16088 datasets. (C, D) Heatmap analysis of shared DEGs enriched in KEGG pathway hsa04141 from the two GSE datasets. DEGs were defined with |log2FC| > 1 and adjusted P-value < 0.05.