Research Paper Volume 12, Issue 24 pp 24651—24670

Downregulated genes by silencing MYC pathway identified with RNA-SEQ analysis as potential prognostic biomarkers in gastric adenocarcinoma

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Figure 2. Level of mRNA and protein expression of TTLL12 (A), CDKN3 (B), CDC16 (C), PTPRA (D), MZT2B (E), and UBE2T (F) in diffuse (n = 103) and intestinal (n = 110) GC tumor samples. Mann – Whitney test was used to compare the relative gene expression levels. In all graphs, the expression in gastric tumors was normalized by matched non-neoplastic gastric tissue. RQ: relative quantification; T: tumor sample; N: normal mucosa sample; The whiskers indicate the minimum and maximum values. red dotted line represents the 1.5 fold-change.