Research Paper Volume 13, Issue 3 pp 3536—3553

Identification of HIPK3 as a potential biomarker and an inhibitor of clear cell renal cell carcinoma

HIPK3 expression is associated with BAP1 mutation. (A) The expression of HIPK3 decreased when BAP1 mutation. (B, C) High expression of HIPK3 is correlate with good OS and DFS of renal cancer between wild-type and mutation subsets of TP53, VHL, BAP1, and PBRM1. OS, overall survival; DFS, disease–free survival; HIPK3, Homeodomain interacting protein kinases 3.

Figure 5. HIPK3 expression is associated with BAP1 mutation. (A) The expression of HIPK3 decreased when BAP1 mutation. (B, C) High expression of HIPK3 is correlate with good OS and DFS of renal cancer between wild-type and mutation subsets of TP53, VHL, BAP1, and PBRM1. OS, overall survival; DFS, disease–free survival; HIPK3, Homeodomain interacting protein kinases 3.