Research Paper Advance Articles

Identification of HIPK3 as a potential biomarker and an inhibitor of clear cell renal cell carcinoma

HIPK3 is downregulated in ccRCC tissues. (A, B) Gene expression levels of HIPK3 in renal cancer tissues. (C) Relative HIPK3 expression was downregulated in renal cancer tissues. (D) Validation of HIPK3 expression in renal cancer with Gene Expression Omnibus (GEO66727, GEO53757). (E) IHC analyses of HIPK3 expression in ccRCC tissues and paracancer tissues. **P

Figure 7. HIPK3 is downregulated in ccRCC tissues. (A, B) Gene expression levels of HIPK3 in renal cancer tissues. (C) Relative HIPK3 expression was downregulated in renal cancer tissues. (D) Validation of HIPK3 expression in renal cancer with Gene Expression Omnibus (GEO66727, GEO53757). (E) IHC analyses of HIPK3 expression in ccRCC tissues and paracancer tissues. **P<0.01 and ****P<0.0001.