Research Paper Volume 13, Issue 3 pp 3536—3553

Identification of HIPK3 as a potential biomarker and an inhibitor of clear cell renal cell carcinoma


Figure 8. Effects of HIPK3 overexpression on cell proliferation, migration, and invasion. (A, B) HIPK3 mRNA and protein expressions were successfully overexpressed in 786-O and A498 cells. (C) Cell counting kit-8 assay detected the effects of HIPK3 overexpression on the proliferation of 786-O and A498 cells. (D, E) Representative images of migration and invasion assays performed using 786-O and A498 cells with transwell and wound healing assay. Data are presented as the mean ± SD from three independent experiments. *P<0.05, **P<0.01, and ***P<0.001.