Research Paper Volume 13, Issue 3 pp 3554—3572

ESRP1 regulates alternative splicing of CARM1 to sensitize small cell lung cancer cells to chemotherapy by inhibiting TGF-β/Smad signaling


Figure 1. ESRP1 positively correlates with overall survival. (A) ESRP1 levels from five paired SCLC tumors (T) and normal (N) tissues were analyzed by western blotting. (B) ESRP1 mRNA levels in SCLC tissues and adjacent noncancerous lung tissues. (C) Kaplan–Meier analyses of the correlations between ESRP1 mRNA level and overall survival in SCLC patients. *, p<0.05; **, p <0.01; ***, p <0.001; ****, p <0.0001.