Research Paper Volume 13, Issue 3 pp 3588—3604

Downregulation of circFASTKD1 ameliorates myocardial infarction by promoting angiogenesis


Figure 8. Proposed mechanism. This investigation has suggested that, by binding to miR-106a, circFASTKD1 induces LATS1 and LATS2 expression and inhibits the YAP pathway, thus suppressing angiogenesis, increasing the infarct size and inhibiting repair in the heart following myocardial infarction.