Research Paper Advance Articles

Downregulation of circFASTKD1 ameliorates myocardial infarction by promoting angiogenesis

Proposed mechanism. This investigation has suggested that, by binding to miR-106a, circFASTKD1 induces LATS1 and LATS2 expression and inhibits the YAP pathway, thus suppressing angiogenesis, increasing the infarct size and inhibiting repair in the heart following myocardial infarction.

Figure 8. Proposed mechanism. This investigation has suggested that, by binding to miR-106a, circFASTKD1 induces LATS1 and LATS2 expression and inhibits the YAP pathway, thus suppressing angiogenesis, increasing the infarct size and inhibiting repair in the heart following myocardial infarction.