Research Paper Advance Articles

Enrichment of branched chain amino acid transaminase 1 correlates with multiple biological processes and contributes to poor survival of IDH1 wild-type gliomas

High BCAT1 expression represents poor survival of IDH1 wild-type glioma patients. Representative survival plots of BCAT1 in glioma patients with IDH wild-type proportion attached from TCGA (A–C) and CGGA (D–F) datasets. (G, H) Boxplots showing the distribution of BCAT1 expression in glioma patients according to IDH1 status from TCGA and CGGA datasets. (I, J) Boxplots showing the distribution of BCAT1 expression in IDH1 mutant, 1p19q codeleted glioma patients and IDH1 mutant, 1p19q non codeleted glioma patients from TCGA and CGGA datasets.

Figure 2. High BCAT1 expression represents poor survival of IDH1 wild-type glioma patients. Representative survival plots of BCAT1 in glioma patients with IDH wild-type proportion attached from TCGA (AC) and CGGA (DF) datasets. (G, H) Boxplots showing the distribution of BCAT1 expression in glioma patients according to IDH1 status from TCGA and CGGA datasets. (I, J) Boxplots showing the distribution of BCAT1 expression in IDH1 mutant, 1p19q codeleted glioma patients and IDH1 mutant, 1p19q non codeleted glioma patients from TCGA and CGGA datasets.