Figure 2. KEGG pathway enrichment analysis of differentially methylated regions. Totally 14 pathways were enriched. (A) KEGG pathway enriched from the hypermethylated regions in SCA3/MJD mice compared to controls. (B) KEGG pathways enriched from the hypomethylated regions in SCA3/MJD mice compared to controls. The major pathways were involved in the pathway for tumorigenesis and amino acid biosynthesis.