Research Paper Advance Articles

Key microRNAs and hub genes associated with poor prognosis in lung adenocarcinoma

Volcano plot of gene expression profile data in LUAD and normal samples and the heatmap of the overlapping DEGs. (A) Volcano plot of GSE74190. (B) Volcano plot of GSE31908. (C) Volcano plot of GSE10072. (D) Volcano plot of GSE43458. (E) Venn diagram of the upregulated overlapping DEGs. (F) Venn diagram of the downregulated overlapping DEGs. (G) Heatmap of the overlapping DEGs. Green represents a low fold change (FC) value, and red represents a high fold change FC value. Each column represents one dataset, and each row represents one gene. The number in each rectangle represents the FC in LUAD samples compared with normal samples. The gradual color change from red to green represents the changing process from upregulation to downregulation.

Figure 1. Volcano plot of gene expression profile data in LUAD and normal samples and the heatmap of the overlapping DEGs. (A) Volcano plot of GSE74190. (B) Volcano plot of GSE31908. (C) Volcano plot of GSE10072. (D) Volcano plot of GSE43458. (E) Venn diagram of the upregulated overlapping DEGs. (F) Venn diagram of the downregulated overlapping DEGs. (G) Heatmap of the overlapping DEGs. Green represents a low fold change (FC) value, and red represents a high fold change FC value. Each column represents one dataset, and each row represents one gene. The number in each rectangle represents the FC in LUAD samples compared with normal samples. The gradual color change from red to green represents the changing process from upregulation to downregulation.