Research Paper Volume 13, Issue 3 pp 3742—3762

Key microRNAs and hub genes associated with poor prognosis in lung adenocarcinoma

Expression levels of eight hub genes in human lung adenocarcinoma. (A) SPP1; (B) COL3A1; (C) COL1A1; (D) VWF; (E) CDH5; (F) TEK; (G) PECAM1; and (H) EDN1. The gray and red boxes represent normal and cancer tissues, respectively. The expression data are first log2(TPM+1) transformed for differential analysis, and the log2FC is defined as median (Tumor, T)-median (Normal, N). *P

Figure 7. Expression levels of eight hub genes in human lung adenocarcinoma. (A) SPP1; (B) COL3A1; (C) COL1A1; (D) VWF; (E) CDH5; (F) TEK; (G) PECAM1; and (H) EDN1. The gray and red boxes represent normal and cancer tissues, respectively. The expression data are first log2(TPM+1) transformed for differential analysis, and the log2FC is defined as median (Tumor, T)-median (Normal, N). *P < 0.05, T vs N. Abbreviations: FC, fold change; TPM, transcript per kilobase million.