Research Paper Advance Articles

Cell lineage-specific methylome and genome alterations in gout

Pathway analysis of differentially methylated genes. The top 20 pathways of differentially methylated genes in monocytes (A), eosinophils (B), neutrophils (C), NK cells (D), B cells (E), CD4+ T cells (F) and CD8+ T cells (G) revealed by Ingenuity Pathway Analysis and corresponding P values are shown. The dashed orange lines represent P values of 0.05. Pathways related to interleukin-1 (IL-1) are highlighted with red.

Figure 1. Pathway analysis of differentially methylated genes. The top 20 pathways of differentially methylated genes in monocytes (A), eosinophils (B), neutrophils (C), NK cells (D), B cells (E), CD4+ T cells (F) and CD8+ T cells (G) revealed by Ingenuity Pathway Analysis and corresponding P values are shown. The dashed orange lines represent P values of 0.05. Pathways related to interleukin-1 (IL-1) are highlighted with red.