Research Paper Volume 13, Issue 3 pp 4138—4156

Diagnostic and prognostic values of AKR1C3 and AKR1D1 in hepatocellular carcinoma

The results of AKR1C3 and AKR1D1 lentiviral transfection. (A) Relative protein expression of AKR1C3 and AKR1D1 in HCC cell lines. (B) The protein level of AKR1C3 in SMMC-7721 cells after the knockdown. (C) The cell viability of sh-AKR1C3 and control groups. (D) The protein level of AKR1D1 in HuH-7 cells after overexpression. (E) The cell viability of AKR1D1-1 and control groups. (F, G) The protein levels of MEK1, p-MEK1, p-Erk1/2, AR, and ID1 in the AKR1C3 knockdown and AKR1D1 overexpression cells.

Figure 6. The results of AKR1C3 and AKR1D1 lentiviral transfection. (A) Relative protein expression of AKR1C3 and AKR1D1 in HCC cell lines. (B) The protein level of AKR1C3 in SMMC-7721 cells after the knockdown. (C) The cell viability of sh-AKR1C3 and control groups. (D) The protein level of AKR1D1 in HuH-7 cells after overexpression. (E) The cell viability of AKR1D1-1 and control groups. (F, G) The protein levels of MEK1, p-MEK1, p-Erk1/2, AR, and ID1 in the AKR1C3 knockdown and AKR1D1 overexpression cells.