Research Paper Volume 13, Issue 3 pp 4199—4214

Long non-coding RNA (LncRNA) HOTAIR regulates BMP9-induced osteogenic differentiation by targeting the proliferation of mesenchymal stem cells (MSCs)

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Figure 5.

Silencing HOTAIR expression promotes the proliferative capability of iMAD cells. (A) Subconfluent iMAD-KD and iMAD-Ctrl were infected with Ad-BMP9 or Ad-GFP and fixed for Crystal violet staining at indicated time points. (B, C) The stained cells were dissolved and quantitatively determined at A590nm. Representative images are shown. “*” p < 0.05, iMAD-Ctrl+GFP group vs iMAD-KD+GFP group. “**” p < 0.05, iMAD-Ctrl+BMP9 group vs iMAD-KD+BMP9 group.