Research Paper Volume 13, Issue 3 pp 4242—4257

Oxaliplatin induces the PARP1-mediated parthanatos in oral squamous cell carcinoma by increasing production of ROS

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Figure 3. Oxaliplatin caused mitochondrial damage in OSCC cells. (A, C) Representative images of JC-1 staining in CAL27 and SCC25 cells treated with oxaliplatin. (B, D) The fluorescence ratio of monomeric JC-1/ aggregate JC-1 in CAL27 and SCC25 cells treated with oxaliplatin. * p<0.05, **p<0.01.