Research Paper Volume 13, Issue 3 pp 4388—4408

Lumican inhibits immune escape and carcinogenic pathways in colorectal adenocarcinoma

LUM expression correlated with macrophage polarization in COAD. Markers include (A) CCL2 and IL10 of TAMs (tumor-associated macrophages); (B) FOXP3, CCR8, and TGFB1 of Tregs; (C) CD163, VSIG4, and MS4A4A of M2 macrophages; (D) HLA-DPB1, CD1C, NRP1, and ITGAX of DCs; (E) CD86 and CSF1R of monocytes; (F) C1QC and SPP1 of TAM subtypes.

Figure 5. LUM expression correlated with macrophage polarization in COAD. Markers include (A) CCL2 and IL10 of TAMs (tumor-associated macrophages); (B) FOXP3, CCR8, and TGFB1 of Tregs; (C) CD163, VSIG4, and MS4A4A of M2 macrophages; (D) HLA-DPB1, CD1C, NRP1, and ITGAX of DCs; (E) CD86 and CSF1R of monocytes; (F) C1QC and SPP1 of TAM subtypes.