Research Paper Volume 13, Issue 3 pp 4482—4502

Identification of downstream signaling cascades of ACK1 and prognostic classifiers in non-small cell lung cancer

Prognostic values of the gene signature comprising ACK1 and the 14 genes of the most significant module in the TCGA lung cancer patients. Patients were classified into low (green) and high (red) risk groups according to risk scores. Heatmaps of 15 gene expression profiles in the low and high risk LUAD (A) and LUSC (B) patients. Comparison of the 15 gene expression levels between high (blue) and low (red) risk groups in LUAD (C) and LUAD (D). Univariate (upper panel) and multivariate (lower panel) Cox regression analyses in LUAD (E) and LUSC (F).

Figure 6. Prognostic values of the gene signature comprising ACK1 and the 14 genes of the most significant module in the TCGA lung cancer patients. Patients were classified into low (green) and high (red) risk groups according to risk scores. Heatmaps of 15 gene expression profiles in the low and high risk LUAD (A) and LUSC (B) patients. Comparison of the 15 gene expression levels between high (blue) and low (red) risk groups in LUAD (C) and LUAD (D). Univariate (upper panel) and multivariate (lower panel) Cox regression analyses in LUAD (E) and LUSC (F).