Research Paper Volume 13, Issue 4 pp 5020—5033

Toxic effect of titanium dioxide nanoparticles on corneas in vitro and in vivo

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Figure 3. TiO2 NPs caused apoptosis and cell cycle arrest of corneal endothelial cells. Apoptosis analysis (A) and cell cycle analysis (B) of TiO2 NPs-treated primary corneal endothelial cells by using flow cytometry. *P<0.05, **P<0.01, ***P<0.001.