Research Paper Volume 12, Issue 24 pp 24894—24913

Obesity induced by high-fat diet is associated with critical changes in biological and molecular functions of mesenchymal stromal cells present in visceral adipose tissue

Figure 6. Overexpressed proteins in HFD-MSCs associated with senescence. The picture shows the overexpressed (in red) and downregulated (in black) proteins in the proteomes and secretomes of HFD-MSCs compared to ND-MSCs. The differences in expression are expressed as LogFC. The column “Upregulated in senescence” indicates the proteins for which expression is upregulated in senescent cells, according to SeneQuest ( and PubMed (