Research Paper Volume 13, Issue 5 pp 6606—6624

Coexpression of HOXA6 and PBX2 promotes metastasis in gastric cancer

HOXA6 is highly expressed in GC tissues predicted unfavourable prognosis in GC patients. (A) We detected HOXA6 expression in GC tissues and adjacent normal tissues by TMAs. Representative views are shown. (B) HOXA6 protein scores in NT and GC as detected using a TMA-based assay. NT, normal tissue; GC, gastric cancer (C) The overall survival times of 85 patients with GC categorized as “low HOXA6” or “high HOXA6” groups after surgery are compared. (D, E) HOXA6 expression in patients with early-stage GC (D) and late-stage GC (E). Log-rank test was employed to calculate the statistical significance. Scale bars in A represent 25 μm.

Figure 2. HOXA6 is highly expressed in GC tissues predicted unfavourable prognosis in GC patients. (A) We detected HOXA6 expression in GC tissues and adjacent normal tissues by TMAs. Representative views are shown. (B) HOXA6 protein scores in NT and GC as detected using a TMA-based assay. NT, normal tissue; GC, gastric cancer (C) The overall survival times of 85 patients with GC categorized as “low HOXA6” or “high HOXA6” groups after surgery are compared. (D, E) HOXA6 expression in patients with early-stage GC (D) and late-stage GC (E). Log-rank test was employed to calculate the statistical significance. Scale bars in A represent 25 μm.