Research Paper Volume 13, Issue 4 pp 5297—5311

LncRNA MIR205HG regulates melanomagenesis via the miR-299-3p/VEGFA axis

Silencing of MIR205HG promotes apoptosis in melanoma cells. Representative FACS plots show Annexin-V FITC (X-axis) and propidium iodide (PI; Y-axis) stained (A, B) control and MIR205HG shRNA2-transfected A375 cells and (C, D) control and MIR205HG shRNA2-transfected MNT-1 cells. The apoptotic rate was calculated based on the percentage of Annexin-V+ PI+ and Annexin-V+ PI- cells in each group. All experiments were performed thrice. **P##P

Figure 3. Silencing of MIR205HG promotes apoptosis in melanoma cells. Representative FACS plots show Annexin-V FITC (X-axis) and propidium iodide (PI; Y-axis) stained (A, B) control and MIR205HG shRNA2-transfected A375 cells and (C, D) control and MIR205HG shRNA2-transfected MNT-1 cells. The apoptotic rate was calculated based on the percentage of Annexin-V+ PI+ and Annexin-V+ PI- cells in each group. All experiments were performed thrice. **P<0.01 compared to the control; ##P<0.01 vs. MIR205HG shRNA2-transfected cells.