Research Paper Volume 13, Issue 1 pp 89—103

Further assessment of Salvia haenkei as an innovative strategy to counteract skin photo-aging and restore the barrier integrity

Effect of Salvia haenkei extract 0.01-0.1-1-10 μg/ml on p21 (A) and p27 (B) mRNA levels in HaCaT cells exposed and not exposed to UVB radiation (30 KJ/m2). Results are normalized to GAPDH, expressed as ratio of treatment vs control not exposed to UVB, and are the mean ± SEM of 3 independent experiments. *p vs control-UVB; §p p vs control+UVB.

Figure 4. Effect of Salvia haenkei extract 0.01-0.1-1-10 μg/ml on p21 (A) and p27 (B) mRNA levels in HaCaT cells exposed and not exposed to UVB radiation (30 KJ/m2). Results are normalized to GAPDH, expressed as ratio of treatment vs control not exposed to UVB, and are the mean ± SEM of 3 independent experiments. *p < 0.05, treatment vs control-UVB; §p < 0.05, §§p < 0.01treatment vs control+UVB.