Research Paper Volume 13, Issue 4 pp 5403—5414

RNF168 is highly expressed in esophageal squamous cell carcinoma and contributes to the malignant behaviors in association with the Wnt/β-catenin signaling pathway

(A) and (B) Enrichment analysis of differentially expressed genes in 184 cases of esophageal cancer from the TCGA database; (C) Pathway enrichment analysis; (D) correlation between WNT3A and RNF168 mRNA levels; (E) Wnt/β-catenin signaling pathway protein component levels in ECA-109 and EC9706 cells after transduction; (F) PPI network for RNF168. (G) RNF168 and ATM expression by Western blot.

Figure 5. (A) and (B) Enrichment analysis of differentially expressed genes in 184 cases of esophageal cancer from the TCGA database; (C) Pathway enrichment analysis; (D) correlation between WNT3A and RNF168 mRNA levels; (E) Wnt/β-catenin signaling pathway protein component levels in ECA-109 and EC9706 cells after transduction; (F) PPI network for RNF168. (G) RNF168 and ATM expression by Western blot.