Research Paper Volume 13, Issue 4 pp 5475—5484

LncRNA PCGEM1 contributes to malignant behaviors of glioma by regulating miR-539-5p/CDK6 axis

PCGEM1 was the ceRNA for miR-539-5p. (A, B) Relative expression of miR-539-5p after PCGEM1knockdown or overexpression. (C) Predicted binding site in PCGEM1 with miR-539-5p through miRDB. (D) Luciferase reporter assay was performed. (E) Correlation between PCGEM1 and miR-539-5p expressions in glioma tissues (r=-0.6704; PP

Figure 3. PCGEM1 was the ceRNA for miR-539-5p. (A, B) Relative expression of miR-539-5p after PCGEM1knockdown or overexpression. (C) Predicted binding site in PCGEM1 with miR-539-5p through miRDB. (D) Luciferase reporter assay was performed. (E) Correlation between PCGEM1 and miR-539-5p expressions in glioma tissues (r=-0.6704; P<0.001; R square=0.4494). *P<0.05.