Research Paper Volume 13, Issue 4 pp 5475—5484

LncRNA PCGEM1 contributes to malignant behaviors of glioma by regulating miR-539-5p/CDK6 axis


Figure 4. MiR-539-5p targeted CDK6. (A, B) Relative expression of CDK6 after transfection with miR-539-5p inhibitors or mimics. (C) Predicted binding site in CDK6 with miR-539-5p through TargetScan. (D, E) Luciferase reporter assay and RIP assay were conducted to validate the interaction between miR-539-5p and CDK6. *P<0.05.