Research Paper Volume 13, Issue 4 pp 5506—5524

Comprehensive analysis of prognostic immune-related genes in the tumor microenvironment of colorectal cancer

Identification of differentially expressed genes based on the immune scores, stromal scores, and tumor purity of CRC patients. (A) Volcano plots of the DEGs based on stromal scores. (B) Volcano plots of the DEGs based on immune scores. (C) Volcano plots of the DEGs based on tumor purity. (D) Venn diagram shows the numbers of upregulated genes in the immune score, stromal score and tumor purity groups as well as the upregulated genes that are common among the three groups. (E) Venn diagram shows the numbers of downregulated genes in immune score, stromal score and tumor purity groups as well as the downregulated genes that are common among the three groups.

Figure 2. Identification of differentially expressed genes based on the immune scores, stromal scores, and tumor purity of CRC patients. (A) Volcano plots of the DEGs based on stromal scores. (B) Volcano plots of the DEGs based on immune scores. (C) Volcano plots of the DEGs based on tumor purity. (D) Venn diagram shows the numbers of upregulated genes in the immune score, stromal score and tumor purity groups as well as the upregulated genes that are common among the three groups. (E) Venn diagram shows the numbers of downregulated genes in immune score, stromal score and tumor purity groups as well as the downregulated genes that are common among the three groups.