Research Paper Volume 13, Issue 4 pp 5525—5538

QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway

Effect of QiShen YiQi Pill (QSYQ) on expression of Beclin-1, LC3B, and p62 in rats. (A) The Beclin-1 mRNA expression for each group. (B) The LC3B mRNA expression for each group. (C) The p62 mRNA expression for each group. (D) The relative protein level of Beclin-1 in the myocardium. (E) The relative protein level of LC3-II/LC3-II in the myocardium. (F) The relative protein level of p62 in the myocardium. (G) Beclin-1, LC3-II, LC3-I, and p62 expression in the myocardium of rats in each group as detected by western blot. Data are expressed as mean ± SD, *P#P

Figure 5. Effect of QiShen YiQi Pill (QSYQ) on expression of Beclin-1, LC3B, and p62 in rats. (A) The Beclin-1 mRNA expression for each group. (B) The LC3B mRNA expression for each group. (C) The p62 mRNA expression for each group. (D) The relative protein level of Beclin-1 in the myocardium. (E) The relative protein level of LC3-II/LC3-II in the myocardium. (F) The relative protein level of p62 in the myocardium. (G) Beclin-1, LC3-II, LC3-I, and p62 expression in the myocardium of rats in each group as detected by western blot. Data are expressed as mean ± SD, *P<0.01, #P<0.05.