Research Paper Volume 13, Issue 4 pp 5650—5673

Synergistic inflammatory signaling by cGAS may be involved in the development of atherosclerosis

Results of analysis of the PPI network associated with atherosclerosis. (A) The PPI network of DEGs associated with atherosclerosis. The green circles represent down-regulated DEG-encoded proteins and the red circles represent upregulated DEG-encoded proteins. The size of the circle indicates the abundance of gene expression. (B) The top 10 hub genes in the PPI network by MCC method. (C–E) A function subnet module analysis performed by ClueGO. Terms are presented in different colors. PPI, Protein–Protein Interaction.

Figure 7. Results of analysis of the PPI network associated with atherosclerosis. (A) The PPI network of DEGs associated with atherosclerosis. The green circles represent down-regulated DEG-encoded proteins and the red circles represent upregulated DEG-encoded proteins. The size of the circle indicates the abundance of gene expression. (B) The top 10 hub genes in the PPI network by MCC method. (CE) A function subnet module analysis performed by ClueGO. Terms are presented in different colors. PPI, Protein–Protein Interaction.