Research Paper Volume 13, Issue 4 pp 5892—5905

Circ_ 0115744 acts as miR-144 sponge to promote and predict the metastasis of colorectal cancer

miR-144 directly targeted EZH2 (A) Relative expression of miR-144 in tissues samples of CRLM and CRC. (B) Pearson correlation analysis for circ

Figure 5. miR-144 directly targeted EZH2 (A) Relative expression of miR-144 in tissues samples of CRLM and CRC. (B) Pearson correlation analysis for circ_0115744/miR-144/EZH2 in tissues. Data were presented as plot of the mean with SD with log-transformed. (C) Detailed binding site for miR-144 and EZH2. (D) Dual-luciferase reporter assay in cells treated with EZH2 3’UTR and candidate miR-144 mimics. Data were presented as plot of the mean with SEM. *Indicated P < 0.05.