Research Paper Volume 13, Issue 5 pp 6662—6680

The novel roles of virus infection-associated gene CDKN1A in chemoresistance and immune infiltration of glioblastoma

Venn diagrams of gene expression microarray datasets. (A) The 74 co-DEGs in three publicly available datasets including GSE43452, GSE65363 and GSE80729. (B) CDKN1A, MSX1, MYC and CHEK2 were consistently identified between 74 co-DEGs and one HTLV-1 infection-related gene set. Each rectangle represents a dataset. The number in each overlapping region represents the number of differentially expressed genes. The intersection in the middlemost area represents the number of genes that were consistently differentially expressed in all these datasets.

Figure 1. Venn diagrams of gene expression microarray datasets. (A) The 74 co-DEGs in three publicly available datasets including GSE43452, GSE65363 and GSE80729. (B) CDKN1A, MSX1, MYC and CHEK2 were consistently identified between 74 co-DEGs and one HTLV-1 infection-related gene set. Each rectangle represents a dataset. The number in each overlapping region represents the number of differentially expressed genes. The intersection in the middlemost area represents the number of genes that were consistently differentially expressed in all these datasets.