Research Paper Volume 13, Issue 5 pp 6702—6711

The impact of visceral obesity on chronic constipation, inflammation, immune function and cognitive function in patients with inflammatory bowel disease

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Figure 4. Impact of visceral obesity in different sex groups in patients with Crohn’s disease. (A) Impact of visceral obesity on IL-6. Male patients with visceral obesity had higher level of IL-6 compared with male patients without visceral obesity (17.18 ± 10.5 pg/ml, n=11 vs. 7.5 ± 3.02 pg/ml, n=6, P = 0.045). Female patients with visceral obesity tended to have higher level of IL-6 compared with female patients without visceral obesity (14.48 ± 10.66 pg/ml, n=26 vs. 9.83 ± 7.49 pg/ml, n=29, P = 0.065). (B) Impact of visceral obesity on CD4+ T cells. Male patients with visceral obesity had lower level of CD4+ T cells compared with male patients without visceral obesity (32.87 ± 3.03%, n=11 vs. 45.33 ± 2.88%, n=6, P <0.001). Female patients with visceral obesity had lower level of CD4+ T cells compared with female patients without visceral obesity (32.63 ± 3.2%, n=26 vs. 43.72 ± 2.56%, n=29, P <0.001).