Research Paper Volume 13, Issue 5 pp 6945—6956

Silencing of miR-483-5p alleviates postmenopausal osteoporosis by targeting SATB2 and PI3K/AKT pathway

PI3K/AKT signaling is the downstream target for the role of miR-483-5p-SATB2 axis in ovariectomized rats. (A) Western blotting results of the expressions of osteogenic differentiation indicators. (B) Quantitative analysis of the optical density in (A). (C) Western blotting results of the expressions of PI3K/AKT signaling. (D) Quantitative analysis of the optical density in (C). Data were presented as mean ± SD. a p b p c p

Figure 7. PI3K/AKT signaling is the downstream target for the role of miR-483-5p-SATB2 axis in ovariectomized rats. (A) Western blotting results of the expressions of osteogenic differentiation indicators. (B) Quantitative analysis of the optical density in (A). (C) Western blotting results of the expressions of PI3K/AKT signaling. (D) Quantitative analysis of the optical density in (C). Data were presented as mean ± SD. a p < 0.05 versus control group, b p < 0.05 versus model group, c p < 0.05 versus inhibitor group.