Research Paper Volume 13, Issue 5 pp 6999—7019

Integrative analysis of genomic, epigenomic and transcriptomic data identified molecular subtypes of esophageal carcinoma

4 genes as potential biomarkers for the three molecular subtypes. The relationship between gene expression (horizontal) and methylation (vertical) levels (left panel), expression distribution in three iCluster subtypes (middle panel), and overall survival proportions in TCGA and GSE53625 data sets (right panel) were analyzed for (A) GDF15, (B) YBX2, (C) CLDN3 and (D) FAM221A.

Figure 8. 4 genes as potential biomarkers for the three molecular subtypes. The relationship between gene expression (horizontal) and methylation (vertical) levels (left panel), expression distribution in three iCluster subtypes (middle panel), and overall survival proportions in TCGA and GSE53625 data sets (right panel) were analyzed for (A) GDF15, (B) YBX2, (C) CLDN3 and (D) FAM221A.