Research Paper Volume 13, Issue 5 pp 7035—7051

ENAM gene associated with T classification and inhibits proliferation in renal clear cell carcinoma

ENAM regulates the proliferation of renal cancer cells. (A, B) Upregulation of ENAM significantly increased the expression of Bax and Cas3, yet decreased the expression of Bcl-2; (C) Upregulation of ENAM reduced the mean colony number in the colony formation assay; (D) MTT assays revealed that upregulation of ENAM significantly reduced the cell viability. Abbreviations: NS: P>0.05; *: P

Figure 7. ENAM regulates the proliferation of renal cancer cells. (A, B) Upregulation of ENAM significantly increased the expression of Bax and Cas3, yet decreased the expression of Bcl-2; (C) Upregulation of ENAM reduced the mean colony number in the colony formation assay; (D) MTT assays revealed that upregulation of ENAM significantly reduced the cell viability. Abbreviations: NS: P>0.05; *: P<0.05; **: P<0.01; ***: P<0.001.