Research Paper Volume 13, Issue 5 pp 7035—7051

ENAM gene associated with T classification and inhibits proliferation in renal clear cell carcinoma

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Figure 7. ENAM regulates the proliferation of renal cancer cells. (A, B) Upregulation of ENAM significantly increased the expression of Bax and Cas3, yet decreased the expression of Bcl-2; (C) Upregulation of ENAM reduced the mean colony number in the colony formation assay; (D) MTT assays revealed that upregulation of ENAM significantly reduced the cell viability. Abbreviations: NS: P>0.05; *: P<0.05; **: P<0.01; ***: P<0.001.