Research Paper Volume 13, Issue 5 pp 7067—7083

GIT1 protects traumatically injured spinal cord by prompting microvascular endothelial cells to clear myelin debris

GIT1 promotes MECs angiogenesis in vivo. (A, B) Representative IF and quantification of microvessels and MECs at the injury core in the GIT1 WT and KO groups at day 3 and 7 after SCI. Nuclei were counterstained with DAPI (blue). Bar = 500 μm. (C, D) Representative western blots of CD31 and VEGF and the semiquantification of relative expression levels of CD31 and VEGF. N = 5 animals in each group. *p **p ***p

Figure 4. GIT1 promotes MECs angiogenesis in vivo. (A, B) Representative IF and quantification of microvessels and MECs at the injury core in the GIT1 WT and KO groups at day 3 and 7 after SCI. Nuclei were counterstained with DAPI (blue). Bar = 500 μm. (C, D) Representative western blots of CD31 and VEGF and the semiquantification of relative expression levels of CD31 and VEGF. N = 5 animals in each group. *p < 0.05, **p < 0.01, ***p < 0.001.