Research Paper Volume 13, Issue 5 pp 7330—7349

The aging-related risk signature in colorectal cancer

In the 50 hallmark gene sets, we conducted GSEA between the high- and low-risk groups. (A) Significant enrichment of 27 hallmark gene sets in the high-risk group of training group TCGA; (B) Significant enrichment of 18 hallmark gene sets in the low-risk group of the training group; (C) Significant enrichment of 24 hallmark gene sets in the high-risk group of testing group GSE39582; (D) Significant enrichment of 9 hallmark gene sets in the low-risk group of the testing group. Dark black represented the enrichment results common to both datasets (Nominal P-value

Figure 11. In the 50 hallmark gene sets, we conducted GSEA between the high- and low-risk groups. (A) Significant enrichment of 27 hallmark gene sets in the high-risk group of training group TCGA; (B) Significant enrichment of 18 hallmark gene sets in the low-risk group of the training group; (C) Significant enrichment of 24 hallmark gene sets in the high-risk group of testing group GSE39582; (D) Significant enrichment of 9 hallmark gene sets in the low-risk group of the testing group. Dark black represented the enrichment results common to both datasets (Nominal P-value < 5% and FDR q-value<25%).