Research Paper Volume 13, Issue 5 pp 7397—7415

Prognostic significance of epigenetic regulatory gene expression in patients with non-small-cell lung cancer

Epigenetic regulatory protein expression in NSCLC and normal lung tissues. The Human Protein Atlas database analysis results show the expression levels of UHRF1, EZH2, TTF2, PCNA, WHSC1, SUV39H2 and RAD54L proteins in NSCLC and normal lung tissues. UHRF1, EZH2, TTF2, PCNA, and WHSC1 protein levels were significantly upregulated in NSCLC tissues (A–C, E–F). SUV39H2 and RAD54L proteins were similar in the NSCLC and normal lung tissues (D, G).

Figure 4. Epigenetic regulatory protein expression in NSCLC and normal lung tissues. The Human Protein Atlas database analysis results show the expression levels of UHRF1, EZH2, TTF2, PCNA, WHSC1, SUV39H2 and RAD54L proteins in NSCLC and normal lung tissues. UHRF1, EZH2, TTF2, PCNA, and WHSC1 protein levels were significantly upregulated in NSCLC tissues (AC, EF). SUV39H2 and RAD54L proteins were similar in the NSCLC and normal lung tissues (D, G).