Research Paper Volume 13, Issue 5 pp 7397—7415

Prognostic significance of epigenetic regulatory gene expression in patients with non-small-cell lung cancer

Frequency of mutations in epigenetic regulatory genes in NSCLC samples. The cBioportal database analysis shows that the frequency of mutations in UHRF1, EZH2, TTF2, SUV39H2, PCNA, WHSC1/NSD2 and RAD54L were 0.5%, 2.8%, 3%, 1.3%, 1.4%, 2.4% and 1.7%, respectively, in NSCLC samples (n=1144).

Figure 7. Frequency of mutations in epigenetic regulatory genes in NSCLC samples. The cBioportal database analysis shows that the frequency of mutations in UHRF1, EZH2, TTF2, SUV39H2, PCNA, WHSC1/NSD2 and RAD54L were 0.5%, 2.8%, 3%, 1.3%, 1.4%, 2.4% and 1.7%, respectively, in NSCLC samples (n=1144).