Research Paper Volume 13, Issue 4 pp 6091—6102

Circ_0000527 promotes osteosarcoma cell progression through modulating miR-646/ARL2 axis

Ectopic expression of circ

Figure 3. Ectopic expression of circ_0000527 induced cell growth, cell cycle progression and invasion. (A) The level of circ_0000527 was determined by a qRT-PCR assay. (B) The elevated expression of circ_0000527 enhanced ki-67 expression in MG-63 cells. (C) The level of CDK2 was determined using qRT-PCR analysis. (D) The ectopic expression of circ_0000527 induced cell growth in MG-63 cells. (E) The overexpression of circ_0000527 induced cell cycle progression in MG-63 cells. *p<0.05, ** p<0.01, ***p<0.001.