Research Paper Volume 13, Issue 4 pp 6115—6133

Identification of miRNAs as diagnostic and prognostic markers in hepatocellular carcinoma

Verification of let-7e expression in transfected HCC cells. (A) Expression of let-7e was significantly upregulated in HepG2 and Hep3B HCC cells transfected with let-7e mimic compared with those transfected with control mimic. (B) Expression of let-7e was significantly downregulated in HepG2 and Hep3B HCC cells transfected with let-7e inhibitor compared with those transfected with control inhibitor (*PPP

Figure 4. Verification of let-7e expression in transfected HCC cells. (A) Expression of let-7e was significantly upregulated in HepG2 and Hep3B HCC cells transfected with let-7e mimic compared with those transfected with control mimic. (B) Expression of let-7e was significantly downregulated in HepG2 and Hep3B HCC cells transfected with let-7e inhibitor compared with those transfected with control inhibitor (*P<0.05, **P<0.01, ***P<0.001). NC mimic–transfected and NC inhibitor-transfected cells were the control group in all experiments.