Research Paper Volume 13, Issue 6 pp 8248—8275

Transcriptome profiling reveals target in primary myelofibrosis together with structural biology study on novel natural inhibitors regarding JAK2

(A) PCA plot among 3 datasets before eliminating “batch effects”. PCA, principal component analysis. (B) PCA plot among 3 datasets after eliminating “batch effects”. (C) Generated QQ plot and density plot after eliminating “batch effects”. (D) Validation of box plot of GSE26049 after eliminating “batch effects”, results illustrated that the median of each sample expression was on a straight line, indicating that the operation of removing “batch effects” did not affect the expression of each dataset.

Figure 3. (A) PCA plot among 3 datasets before eliminating “batch effects”. PCA, principal component analysis. (B) PCA plot among 3 datasets after eliminating “batch effects”. (C) Generated QQ plot and density plot after eliminating “batch effects”. (D) Validation of box plot of GSE26049 after eliminating “batch effects”, results illustrated that the median of each sample expression was on a straight line, indicating that the operation of removing “batch effects” did not affect the expression of each dataset.